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Evaluation of femoral perfusion in a rabbit model of steroid‐induced osteonecrosis by dynamic contrast‐enhanced mri with a high magnetic field MRI system 下载免费PDF全文
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Ligong Wang PhD Ravinder R. Regatte PhD 《Journal of magnetic resonance imaging : JMRI》2015,41(3):586-600
Magnetic resonance imaging (MRI) offers the direct visualization of the human musculoskeletal (MSK) system, especially all diarthrodial tissues including cartilage, bone, menisci, ligaments, tendon, hip, synovium, etc. Conventional MRI techniques based on T1‐ and T2‐weighted, proton density (PD) contrast are inconclusive in quantifying early biochemically degenerative changes in MSK system in general and articular cartilage in particular. In recent years, quantitative MR parameter mapping techniques have been used to quantify the biochemical changes in articular cartilage, with a special emphasis on evaluating joint injury, cartilage degeneration, and soft tissue repair. In this article we focus on cartilage biochemical composition, basic principles of T1ρ MRI, implementation of T1ρ pulse sequences, biochemical validation, and summarize the potential applications of the T1ρ MRI technique in MSK diseases including osteoarthritis (OA), anterior cruciate ligament (ACL) injury, and knee joint repair. Finally, we also review the potential advantages, challenges, and future prospects of T1ρ MRI for widespread clinical translation. J. Magn. Reson. Imaging 2015;41:586–600. © 2014 Wiley Periodicals, Inc. 相似文献
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Sujin Kim Joon Woo Lee Jee Won Chai Hye Jin Yoo Yusuhn Kang Jiwoon Seo Joong Mo Ahn Heung Sik Kang 《Korean journal of radiology》2015,16(6):1294-1302
ObjectiveThe purpose of this study was to evaluate the reliability of a new magnetic resonance imaging (MRI) grading system for cervical neural foraminal stenosis (NFS).ResultsFor the distinction among the three individual grades at all six neural foramina, the ICC ranged from 0.68 to 0.73, indicating fair to good reproducibility. The percentage agreement ranged from 60.2% to 70.6%, and the kappa values (κ = 0.50-0.58) indicated fair to moderate agreement. The percentages of intraobserver agreement ranged from 85.4% to 93.8% (κ = 0.80-0.92), indicating near perfect agreement.ConclusionThe new MRI grading system shows sufficient interobserver and intraobserver agreement to reliably assess cervical NFS. 相似文献
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马淼 《中华医学图书情报杂志》2015,24(8):39-42
概述了信息技术基础架构库(ITIL)的基本情况,从运维管理、事件管理、任务管理、问题管理等方面介绍了ITIL服务管理流程及其在北京妇产医院的应用,并对应用效果进行了评述,对存在的问题提出了建议。 相似文献
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针对传统航空医学声像资料管理方式单一落后的实际情况,通过采用功能强大、性能先进的现代媒体资产管理技术,全面整合空军航空医学研究各类声像数据资源,构建了规模较大、资料丰富、检索高效、运行安全的军事航空医学声像信息管理系统。该系统实现了声像信息管理科学化、规范化、数字化和网络化,进一步提升了声像服务整体实力和保障效能。 相似文献
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介绍了现阶段卫生信息化建设的人才需求、医学院校信息管理与信息系统专业毕业的就业形势和毕业论文撰写教学的重要性,重点分析了毕业论文撰写教学存在的问题,并以蚌埠医学院为例,有针对性地提出了具体改进措施,构建了基于成长性评价思想的新型毕业论文撰写教学模式。 相似文献
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Johanna I Westbrook Elena Gospodarevskaya Ling Li Katrina L Richardson David Roffe Maureen Heywood Richard O Day Nicholas Graves 《J Am Med Inform Assoc》2015,22(4):784-793
Objective To conduct a cost–effectiveness analysis of a hospital electronic medication management system (eMMS).Methods We compared costs and benefits of paper-based prescribing with a commercial eMMS (CSC MedChart) on one cardiology ward in a major 326-bed teaching hospital, assuming a 15-year time horizon and a health system perspective. The eMMS implementation and operating costs were obtained from the study site. We used data on eMMS effectiveness in reducing potential adverse drug events (ADEs), and potential ADEs intercepted, based on review of 1 202 patient charts before (n = 801) and after (n = 401) eMMS. These were combined with published estimates of actual ADEs and their costs.Results The rate of potential ADEs following eMMS fell from 0.17 per admission to 0.05; a reduction of 71%. The annualized eMMS implementation, maintenance, and operating costs for the cardiology ward were A$61 741 (US$55 296). The estimated reduction in ADEs post eMMS was approximately 80 actual ADEs per year. The reduced costs associated with these ADEs were more than sufficient to offset the costs of the eMMS. Estimated savings resulting from eMMS implementation were A$63–66 (US$56–59) per admission (A$97 740–$102 000 per annum for this ward). Sensitivity analyses demonstrated results were robust when both eMMS effectiveness and costs of actual ADEs were varied substantially.Conclusion The eMMS within this setting was more effective and less expensive than paper-based prescribing. Comparison with the few previous full economic evaluations available suggests a marked improvement in the cost–effectiveness of eMMS, largely driven by increased effectiveness of contemporary eMMs in reducing medication errors. 相似文献